Exosomes
At Refinery Aesthetics & Wellness, we're always looking for the most advanced, results-driven ingredients to bring into our treatment rooms and exosomes are one of the most exciting innovations in skincare science today. Paired with our exclusive Plated skincare line, exosome-infused formulas are designed to work with your skin's own communication systems, helping it look more radiant, resilient, and refreshed.
Whether you add it to your next in-office treatment or bring it home in our Plated product line, exosomes are your skin's newest ally.
WHAT ARE EXOSOMES?
Exosomes are tiny, naturally occurring vesicles released by cells that act as messengers — carrying proteins, growth factors, and signaling molecules from one cell to another. Think of them as your skin's internal courier system, delivering the "instructions" that help cells communicate, repair, and function at their best.
In skincare, cosmetic exosome formulas are designed to support this same kind of cell-to-cell communication topically — helping the skin barrier look stronger, smoother, and more balanced over time. They're often paired with treatments like microneedling or used in standalone serums to complement your skin's natural renewal rhythm.
Refinery uses exosome-based products for their cosmetic benefits only. These products are not intended to diagnose, treat, cure, or prevent any disease or medical condition, and results vary from person to person.
THE SCIENCE BEHIND PLATED
Refinery is proud to offer ( plated )® Skin Science — a skincare line built around Renewosome™ technology, the brand's proprietary approach to harnessing platelet-derived exosomes for the skin and scalp.
Platelet-derived, not synthetic. Unlike plant-derived or lab-engineered alternatives, Plated's exosomes are sourced from platelets, the same cells the body naturally relies on for repair signaling. This sourcing approach is central to how the brand talks about its formulas.
Built on two decades of research. Plated's formulas trace back to research from physician-scientists associated with Mayo Clinic, with the brand citing more than twenty years of underlying research and multiple clinical studies behind the Renewosome platform.
Formulated for the skin barrier and beyond. Each bottle is formulated to deliver a concentrated dose of exosomes — the brand cites concentrations in the trillions per bottle — designed to support the skin's own communication and renewal processes. Plated also markets the line for scalp and hair applications, not just facial skincare.
A range for different needs. The line includes multiple formulas so your provider can match the right product to your skin:
PLATED PRODUCTS AT REFINERY
Daily — a balanced, everyday formula for ongoing hydration and barrier support
Intense — a higher-concentration formula for more visible signs of aging
Calm — formulated for redness-prone, sensitive, or post-procedure skin
Hair Serum — A scalp-targeted exosome serum designed to support the appearance of fuller, thicker, stronger-looking hair and reduce the look of shedding and breakage. Applied directly to the scalp once daily as part of an ongoing hair care routine.
Body Serum Formulated specifically for skin from the neck down (arms, legs, chest, abdomen), where skin is thicker and renews more slowly than facial skin. Designed to support the appearance of firmer, smoother, more even-toned skin and help address crepey or thinning areas.
Shelf-stable by design. Despite containing biologically active material, the formulas are made to remain stable at room temperature, so they fit easily into a daily routine without special storage.
Important: Plated's own marketing includes language around wrinkle reduction, collagen support, and skin "regeneration." As of 2026, no exosome product — regardless of source — has FDA approval for these therapeutic uses, and the FDA has been actively enforcing against structure/function claims in this category. Before this section goes live, please have Refinery's legal/compliance contact confirm which specific claims are appropriate for your website versus reserved for one-on-one consultation conversations with a licensed provider.
In-Treatment Add-On
Ask your Refinery provider to include Plated Exosome Boost during your next microneedling, facial, or resurfacing appointment. Your provider will recommend the right pairing based on your skin goals and treatment plan.
Bring it home
Prefer to build exosomes into your daily routine? Shop the full Plated line online or in-studio and bring clinic-inspired skincare into your everyday routine.
Frequently Asked Questions
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Exosome-based skincare is used cosmetically to support the look and feel of the skin, helping it appear smoother, more hydrated, and more resilient. They're often added to in-clinic treatments or used as part of a daily skincare routine.
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Plated's price reflects what goes into producing it. Platelet-derived exosomes require a specialized sourcing and purification process, and Plated uses a gentle ultrafiltration method (rather than standard centrifugation) to keep each exosome's outer membrane intact — a more delicate, lower-yield process that's necessary for the product to stay stable without refrigeration. Formulas are also manufactured in small, concentrated batches, with some bottles containing over a trillion exosomes, and the brand's pricing reflects years of underlying research and clinical study behind the technology.
We know it's an investment, and we're happy to talk through which product and starting routine makes sense for your goals and budget during a consultation.
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Both are formulated for the face, but they're built for different goals. Daily is the balanced, everyday option, designed for ongoing hydration, barrier support, and long-term skin resilience, and it's a good fit for most people as a foundational routine.
Intense is Plated's most concentrated formula, with a higher exosome concentration aimed at more visible signs of aging, such as deeper lines, uneven tone, and loss of firmness. If you're newer to exosome skincare or want a gentle daily habit, Daily is the natural starting point. If you're targeting more advanced concerns and want the strongest formula available, Intense is the better fit.
Your provider can help you decide and some clients use Daily most days with Intense layered in for extra support.
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Yes — exosome skincare varies quite a bit brand to brand, and it's worth knowing what to look for. The biggest differences come down to source (plant-derived, human platelet–derived, or lab-engineered), exosome concentration per bottle, how the product is purified and stabilized, and how much clinical research backs the formula. Purification method matters more than people expect: some processes damage the exosome's outer membrane, which can affect stability and shelf life. We chose to carry Plated at Refinery because of its platelet-derived sourcing, its gentler purification process, and the clinical research behind it, but as with any category of skincare, quality and claims vary across brands, and we're happy to talk through what sets Plated apart during a consultation.
Revive tired, aging eyes with Plated™ Skin Science Eye Serum—a next-generation regenerative formula powered by platelet-derived exosomes to support visible skin renewal at the cellular level. Designed specifically for the delicate under-eye area, this advanced serum helps reduce the appearance of fine lines, wrinkles, puffiness, and dark circles while improving overall tone and firmness.
Unlike traditional eye creams that simply hydrate, Plated™ Eye Serum works to stimulate collagen production and enhance skin resilience over time. The lightweight, fast-absorbing formula layers seamlessly under makeup and pairs beautifully with in-office treatments like microneedling, lasers, and neurotoxins to optimize results.
Product Benefits:
See results in as little as 4 weeks, including reduced appearance of:
Dark circles & discoloration
Puffy eye bags
Wrinkles, fine lines & crow’s feet
Crepey skin
Excess skin & hooded eyes
Elevate your everyday skincare routine with Plated™ Daily Serum—a lightweight, regenerative formula designed to maintain healthy, youthful-looking skin. Powered by platelet-derived exosomes, this advanced serum supports collagen production, improves skin tone and texture, and enhances overall radiance with consistent use.
Perfect for daily maintenance, Plated™ Daily Serum helps strengthen the skin barrier, calm inflammation, and protect against environmental stressors that accelerate visible aging. Its silky, fast-absorbing texture layers effortlessly under moisturizer and SPF, making it ideal for both morning and evening routines.
Benefits:
Supports collagen and elastin production
Improves skin tone, texture, and brightness
Strengthens and repairs the skin barrier
Helps reduce early signs of aging
Suitable for all skin types
Transform your skin with the power of regenerative science. Plated™ Intense Serum is a clinically advanced formula powered by platelet-derived exosomes designed to support deep skin renewal and visible rejuvenation. This breakthrough serum works at the cellular level to improve the appearance of fine lines, wrinkles, redness, and uneven texture—while strengthening overall skin health.
Unlike traditional anti-aging serums that only target surface hydration, Plated™ Intense Serum helps stimulate collagen and elastin production, enhance skin barrier function, and accelerate recovery following aesthetic treatments such as microneedling, lasers, and chemical peels.
The lightweight, fast-absorbing formula is suitable for all skin types and seamlessly integrates into your daily routine.
Product Benefits:
Reduce the look of fine lines and wrinkles.
Even the appearance of dark spots and redness.
Enhance luminosity and glow.
Gentle for all skin types.
( plated )® HAIR Serum is a scientific breakthrough, harnessing the power of platelet-derived Renewosome™ technology to make your hair look fuller, stronger, and thicker.
Product Benefits:
Reduces the appearance of shedding and breakage
Delivers powerful nutrients to the scalp, increasing the appearance of density, thickness, and fullness
Hydrates the scalp for the appearance of greater volume and natural shine
Invisible-dry formulation for a weightless feel
Unlock visibly smoother, firmer, more radiant-looking skin everywhere with our breakthrough serum, powered by platelet-derived exosomes and designed specifically for the body. Welcome to a new era of total-body renewal.
Clinically proven to:
Visibly tighten crepey, thinning skin
Enhance firmness and elasticity
Support smoother, younger-looking skin
Reduce the look of brown spots and redness
Exosomes
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